A Legacy Mission initiative — free & confidential mental-health support
ASK A QUESTION →
Supplements

Selenium

سیلینیم · selenomethionine
Weak evidence

A narrow safe window and thin mood evidence. Do not stack it.

This is information, not medical advice. This page is information, not medical advice. Nothing here is a prescription, a diagnosis or a recommendation to take anything, and none of it replaces a doctor who knows your history. Supplements are not harmless because they are natural: they interact with prescription medicines, some are unsafe in pregnancy, and a few can cause real damage. Talk to a doctor or pharmacist before starting anything here, especially if you are pregnant, breastfeeding, under 18, have a liver, kidney or heart condition, or take any regular medication. Never stop a prescribed antidepressant to try a supplement instead.

What it is

A trace mineral needed for thyroid hormones and antioxidant enzymes. Brazil nuts are the densest source.

What the research says

Low selenium has been linked with low mood in some population studies, and a few small trials reported improved mood, but the findings do not hold consistently. There is no established role for it in treating depression or anxiety.

What studies have used

Ordinary supplements are around 55 to 200 mcg daily.

Recorded because a person who has decided to try something will find a number somewhere, and a forum's number is worse than a trial's. It is not a recommendation, and the right amount for you depends on things only a doctor who knows your history can weigh.

Who should be careful, and what it interacts with

The gap between enough and too much is unusually small. Chronic excess causes hair loss, brittle nails, garlic breath, nausea and nerve damage. Two or three Brazil nuts already meet the daily requirement, so do not add a supplement on top without reason.

In Pakistan

Usually found inside multivitamins rather than sold alone. Check whether you are already taking it in something else.

Before you take it

Tell your doctor or pharmacist about everything else you take, prescription and herbal both. If you are pregnant, breastfeeding, under 18, or have a liver, kidney, heart or thyroid condition, ask first. And if what brought you here is that you have been feeling low or frightened for weeks, that deserves more than a supplement — ask us anything, anonymously, or talk to us on WhatsApp.

← All supplements for depression

🌙 Talk to our team
0:00