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Medication Side Effects: Dry Mouth, Sore Throat, Chest Pressure

Answered 18 October 2026 at 6:04 pm PKT

If you're experiencing dry mouth, a red sore mouth, chest pressure, or negative thoughts after starting medication, you're not alone. This page explains common side effects, when they might fade, and what to do if they persist.

My mouth is dry and I feel like there's something stuck in my throat. I've been taking medication for a few weeks, and now my mouth is red inside. It hurts, and I feel a slight pressure in my chest. Will these side effects go away? I'm also having negative thoughts that I can't shake off.

Aap are describing some common side effects of antidepressants, and the good news is that most of them do fade with time. The dry mouth and throat discomfort often improve as your body adjusts to the medication. The redness and soreness in your mouth could be due to dryness, so sipping water regularly and using sugar-free gum or lozenges might help. The slight chest pressure could be anxiety, which is also a common early side effect.

What to do about the side effects

  • Try to be patient – these side effects often lessen or go away in a few weeks.
  • Stay hydrated – drink plenty of water to help with the dry mouth.
  • Check with your doctor – if the side effects feel too much, they may adjust your dose or suggest alternatives.

The negative thoughts

These can also be part of the adjustment period, but they might also be the depression itself. Either way, they will pass. The medication needs time to build up in your system, so don’t expect an instant change. In the meantime, try to distract yourself with small, manageable tasks—even just getting up and moving around can help shift your focus. If the negative thoughts feel overwhelming, talk to someone you trust or write them down to get them out of your head.

If the side effects don’t improve or if the negative thoughts feel too heavy, don’t wait—speak to your doctor. They can help you find the right balance.

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Answered by the Depression.pk team
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